原著論文、総説

• 2025年
• 2024年
• 2023年
• 2022年
• 2021年
• 2020年
• 2019年
• 2018年
• 2017年
• 2016年
• 2015年
• 2014年
• 2013年
• 2011年
• 2010年
• 1992年～2009年（PDF．大学時代の研究も含む）

自然免疫制御技術研究組合は自然免疫賦活技術研究会を母体として2010年に設立された。主な研究テーマは、東京大学名誉教授　水野傳一先生を中心とし1988年に大学で始まった自然免疫制御（注：その当時は自然免疫という言葉は人口に膾炙していない）機構研究と自然免疫や炎症を制御する生理活性物質であるLPS研究に端を発し、その後30年余多くの研究者等によって引き継がれた研究成果を基盤として設定されている。そのような背景から、”自然免疫グループ”の研究業績としては、組合設立以前の文献も含め主として自然免疫機構やLPS研究の業績を掲載する。

※2009年（自然免疫制御技術研究組合設立）以前の業績に関しては別ページで開きます（PDFファイル）。

2025年

• Oral and transdermal administration of lipopolysaccharide safely enhances self-healing ability through the macrophage network
  Gen-Ichiro Soma　Masataka Oda　Vindy Tjendana Tjhin　Chie Kohchi　Hiroyuki Inagawa
  Frontires in Immunology, 31 March 2025,Volume 16

2024年

• Baseline data collections of lipopolysaccharide content in 414 herbal extracts and its role in innate immune activation
  Vindy Tjendana Tjhin、 Masataka Oda、 Masashi Yamashita、 Tomoko Iwaki 　Yasuko Fujita 　Koji Wakame　Hiroyuki Inagawa 　Gen-Ichiro Soma
  Sci Rep. 2024 Jul 4;14:15394.
• Development of a Water Soluble Self-assembling Analogue of Vizantin
  Mayo Nakano, Kyohei Sakamoto, Naoto Yamasaki, Yui Asano, Masataka Oda, Hironobu Takahashi, Takashige Kawakami, Masahisa Inoue, Hirofumi Yamamoto
  Chem Pharm Bull. 2024 Volume 72 Issue 2 Pages 226-233
• Lipopolysaccharide Derived from Pantoea agglomerans Directly Promotes the Migration of Human Keratinocytes.
  Hiroyuki Inagawa, Takashi Nishizawa, Chie Kohchi and Gen-Ichiro Soma.
  in vivo.2024, 38:2172-2178.
• Restoration of Spatial Learning Through Oral Administration of Lipopolysaccharides in Diabetes-related Cognitive Dysfunction.
  Hiroyuki Inagawa, Masataka Oda, Vindy Tjendana Tjhin, Chie Kohchi and Gen-Ichiro Soma.
  in vivo. 2024, 38:2190-2196.
• 花粉症有症者に対する脱蝋玄米のアレルギー症状緩和作用.
  －ランダム化プラセボ対称単盲検並行群間比較試験－
  上延麻耶，吉村寛志.
  アレルギーの臨床、2024，Vol. 44(10), No. 602．
• Pantoea agglomerans Lipopolysaccharide Controls Nasal Discomfort—A Placebo-Controlled, Randomized, Double-Blind, Parallel-Group Comparison Trial
  Chie Kohchi, Miyuki Uehiro, Taisuke Fukaya, Norikazu Watanabe, Hiroyuki Inagawa, Genichiro Soma
  Int. J. Transl. Med. 2024, 4(1), 126-139

2023年

• Utility of In Vitro Cellular Models of Low-Dose Lipopolysaccharide in Elucidating the Mechanisms of Anti-Inflammatory and Wound-Healing-Promoting Effects of Lipopolysaccharide Administration In Vivo
  Teruko Honda, Hiroyuki Inagawa
  Int. J. Mol. Sci. 2023, 24(18), 14387
• Suitable Stereoisomers of Vibrioferrin Probes for Iron Uptake of Vibrio Parahaemolyticus
  Ryuichi Sumida, Misa Okuda, Akane Mera, Masaki Inoue, Karanjit Sangita, Kanji Niwa, Tomohiro Tsutsumi, Ryota Sato, Atsushi Nakayama, Naonobu Tanaka, Masataka Oda, and Kosuke Namba.Chemistry Letters Vol.52 No.6(2023)p.477-480
• Foods Containing Pantoea agglomerans LPS Reduce Eye-Nose Allergies—A Double-Blind, Placebo-Controlled, Randomized, Parallel-Group Comparative Pilot Study
  Chie Kohchi , Miyuki Uehiro , Masashi Yamashita , Hiroyuki Inagawa and Gen-Ichiro Soma , . Int. J. Transl. Med. 2023, 3, 299–309.
• Oral route lipopolysaccharide as a potential dementia preventive agent inducing neuroprotective microglia
  HARUKA MIZOBUCHI.Frontiers in Immunology PUBLISHED 09 March 2023
• Oral Administration of Lipopolysaccharide Enhances Insulin Signaling-Related Factors in the KK/Ay Mouse Model of Type 2 Diabetes Mellitus
  Kazushi Yamamoto , Masashi Yamashita , Masataka Oda , Vindy Tjendana Tjhin , Hiroyuki Inagawa and Gen-Ichiro Soma ,Internationai journal of Molecular Science

2022年

• Effect of topical application of lipopolysaccharide on contact hypersensitivity
  Manami Tanaka a, Chie Kohchi b, Hiroyuki Inagawa b, Takeshi Ikemoto c, Mariko Hara-Chikuma
  a,Biochemical and Biophysical Research Communications 586 (2022) 100e106
• Suppression of Inflammatory Cytokine Genes Expression in Vascular Endothelial Cells by Super-low Dose
  Manami Tanaka,Chie Kohchi,Hiroyuki Inagawa,Takeshi Ikemoto,Mariko Hara-Chikuma
  Biochemical and Biophysical Research Communications（2022.1.1、ｐ100-ｐ106）
• Anti-inflammatory and Insulin Signaling Phenotype Induced by Repeated Lipopolysaccharide Stimulation in 3T3-L1 Adipocytes
  KAZUSHI YAMAMOTO, MASASHI YAMASHITA, HIROYUKI INAGAWA, CHIE KOHCHI, and GEN-ICHIRO SOMA. ANTICANCER RESEARCH 42: 3983-3991 (2022)
• Suppression of Inflammatory Cytokine Genes Expression in Vascular Endothelial Cells by Super-low Dose Lipopolysaccharide-activated Macrophages
  TERUKO HONDA and HIROYUKI INAGAWA ANTICANCER RESEARCH 42: 4049-4054 (2022)
• Effect of application of lipopolysaccharide on contact hypersensitivity
  Manami Tanaka,Chie Kohchi,Hiroyuki Inagawa,Takeshi Ikemoto,Mariko Hara-Chikuma.Biochem Biophys Res Commun.
  2022 Jan 1;586:100-106

2021年

• 敏感肌に対するリポポリサッカライドの有効性─バリア機能の改善─.
  河内千恵、竹馬真理子,濵田和人, 筒井翔子, 稲川裕之, 杣源一郎.
  日本化粧品技術者会誌　vol. 55　No. 4　2021.
• Preventionof Diabetes-Associated Cognitive Dysfunction Through Oral Administration of Lipopolysaccharide Derived From Pantoea agglomerans.
  Mizobuchi H, Yamamoto K, Yamashita M, Nakata Y, Inagawa H, Kohchi C, Soma GI. frontiers in Immunology. 2021; 12: 3520.
• Prevention of streptozotocin induced Neuro 2a cell death by C8 B4 microglia transformed with repetitive low dose lipopolysaccharide.
  Mizobuchi H , Yamamoto K, Yamashita K, Inagawa H, Kohchi C, Soma GI.　Mol Med Rep.2021 Oct;24(4):687
• Oral Administration of Lipopolysaccharide Prevents　Cognitive Impairment in Streptozotocin-induced　Diabetic Mice in a Blood Glucose-independent Manner.
  Mizobuchi H, Yamamoto K, Yamashita M, Inagawa H, Kohchi C, Soma GI. Anticancer Res.2021 Aug;41(8):4053-4059
• Regulation of Plasminogen Activator Inhibitor-1 in Adipocytes by Macrophages Activated by Low-dose Lipopolysaccharide.
  Honda T, Inagawa H. Anticancer Res.2021 Aug;41(8): 4071-4076
• Effects of Kumaizasa (Sasa senanensis) Leaf Extract on Innate Immune Regulation in HEK293 Cells and Macrophages.
  Sato K, Tatsunami R, Nakata A, Komatsu KI, Harakawa S, Nedachi T, Haketa K, Inagawa H, Wakame K. Anticancer Res.2021 Aug;41(8): 4093-4100
• 「免疫増強と自然治癒力強化に繋がる新しいLPS素材の未来～コロナ時代の自然免疫機能を考える～」
  杣源一郎. MDB Technology Forecast Report, 2021年3月発行.
• Low-dose lipopolysaccharide as an immune　regulator for homeostasis maintenance in the central nervous system through　transformation to neuroprotective microglia.Mizobuchi H, Soma GI. Neural Regeneration Research. 2021; 16(10): 1928-1934.

2020年

• Useful Cases of Patients With Developmental Disorders Improved by Oral Administration of LPS Derived from Pantoea agglomerans.
  Morishima A, Zhang R, Nagaoka R, Inagawa H. Anticancer Res. 2020 Aug;40(8):4755-4762.
• Mastication Affects Transcriptomes of Mouse Microglia.
  Seki M, Haino A, Ishikawa T, Inagawa H, Soma GI, Terada H, Nashimoto M. Anticancer Res. 2020 Aug;40(8):4719-4727.
• Attempt to Construct an In Vitro Model of Enhancement of Macrophage Phagocytosis Via Continuous Administration of LPS.
  Yamamoto K, Mizobuchi H, Yamashita M, Inagawa H, Kohchi C, Soma GI. Anticancer Res. 2020 Aug;40(8):4711-4717.
• Enhanced Effect of Hyaluronan and Elastin Synthesis in Fibroblasts Through Lipopolysaccharide-activated Macrophages.
  Honda T, Tsutsui S, Kohchi C, Inagawa H. Anticancer Res. 2020 Aug;40(8):4681-4685.
• A Novel Anti-inflammatory Phenotype Transformed by Repetitive Low-dose Lipopolysaccharide in Primary Peritoneal Tissue-resident Macrophages.
  Mizobuchi H, Yamamoto K, Yamashita M, Inagawa H, Kohchi C, Soma GI. Anticancer Res. 2020 Aug;40(8):4457-4464.
• 「LPSの自然免疫活性化と新型コロナウイルス予防効果の可能性」.
  稲川裕之. FOOD STYLE 21, 2020/06/01発行, 277号.
• A unique hybrid characteristic having both pro- and anti-inflammatory phenotype transformed by repetitive low-dose lipopolysaccharide in C8-B4 microglia.
  Mizobuchi H, Yamamoto K, Tsutsui S, Yamashita M, Nakata Y, Inagawa H, Kohchi C, Soma GI. Scientific Reports. 2020; 10: 8945.

2019年

• TLR4 Reactivity of Gluconacetobacter（Gluconacetobacter hansenii GK-1）and Their Synergistic Action with Lactobacillus in Producing Antiallergic Effects.
  Kimura M, Ooe M, Okuyama Y, Yoshioka T, Inagawa H. Jpn Pharmacol Ther. 2019; 47(12): 2001-6.
• 「高齢者の脂質摂取の重要性」.
  山本和史. 食品加工、2019, vol. 39, No. 2.
• Efficacy of continuous ingestion of dewaxed brown rice on the cognitive functions of the residents of elderly welfare facilities: A pilot test using crossover trial.
  Uenobe M, Saika T, Waku N, Ohno M, Inagawa H. Food Sci Nutr. 2019; 7: 3520-3526.
• Pollen Allergy Suppression Effect by the Oral Administration of Acetic Acid Bacteria (Gluconacetobacter hansenii).
  Inagawa H, Nishizawa T, Kochi C, Amano S, Soma GI. Anticancer Res. 2019 Aug;39(8):4511-4516.
• Preventive Effect of Oral Administration of Pantoea agglomerans-derived LPS in a Hypertensive Rat Model Upon Salt Loading.
  Zhang R, Inagawa H, Uchibori S, Masaki T, Kobara H, Soma GI. Anticancer Res. 2019 Aug;39(8):4503-4509.
• Usefulness of Monocytes/macrophages Activated With Low-dose Lipopolysaccharide in Tumor Tissue and Adipose Tissue of Obesity.
  Honda T, Inagawa H. Anticancer Res. 2019 Aug;39(8):4475-4478.
• The Effect of Lipopolysaccharide-containing Moisturizing Cream on Skin Care in Patients With Mild Atopic Dermatitis.
  NAKAI K, KUBOTA Y, SOMA GI and KOHCHI C. In Vivo. 2019 Jan-Feb;33(1):109-114.

2018年

• Lipopolysaccharide-treated Human Monocytes Regulate Gene Expressions After Interactions with Human Adipocytes.
  Honda T and Inagawa H. Biomed J Sci&Tech Res. 2018, 7(4): 5975-5979.
• Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents metabolic dysfunction and Alzheimer's disease-related memory loss in senescence-accelerated prone 8 (SAMP8) mice fed a high-fat diet.
  Kobayashi Y, Inagawa H, Kohchi C, Kazumura K, Tsuchiya H, Miwa T, Okazaki K, Soma GI. PLoS One. 2018 Jun 1;13(6):e0198493.
• Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses.
  Kobayashi Y, Inagawa H, Kohchi C, Kazumura K, Tsuchiya H, Miwa T, Okazaki K, Soma GI. PLoS One. 2018 Mar 27;13(3):e0195008.
  ★ top 10% most cited PLOS ONE papers published in 2018
• Dewaxed Brown Rice Feed Improves Fatty Liver in Obese and Diabetic Model Mice.
  Inagawa H, Saika T, Nishiyama N, Nisizawa T, Kohchi C, Uenobe M, Soma GI. Anticancer Res. 2018 Jul;38(7):4339-4345.
• Evaluation of a Hypertensive Rat Model Using Peripheral Blood Neutrophil Activity, Phagocytic Activity and Oxidized LDL Evaluation.
  Zhang R, Inagawa H, Kazumura K, Tsuchiya H, Miwa T, Morishita N, Uchibori S, Hanashiro J, Masaki T, Kobara H, Soma GI. Anticancer Res. 2018 Jul;38(7):4289-4294.
• Improvement in Protracted Wound Healing by Topical Cream Containing Lipopolysaccharide Derived from Pantoea agglomerans.
  Morishima A, Inagawa H. Anticancer Res. 2018 Jul;38(7):4375-4379.
• 「自然免疫を制御する食品の新しい機能成分としてのLPS」.
  稲川裕之. 食品と開発、vol.53, No.12.

2017年

• Lipopolysaccharides Derived from Pantoea agglomerans Can Promote the Phagocytic Activity of Amyloid β in Mouse Microglial Cells.
  Kobayashi Y, Inagawa H, Kohchi C, Okazaki K, Zhang R, Kobara H, Masaki T, Soma GI. Anticancer Res. 2017 Jul;37(7):3917-3920.
• Improvement Effect of Dewaxed Brown Rice on Constipation in Antibiotic-treated Mice.
  Inagawa H, Saika T, Nishiyama N, Nisizawa T, Kohchi C, Uenobe M, Soma GI. In Vivo. 2017 Jul-Aug;31(4):573-577.
• Measurement of the Phagocytic Activity of Human Peripheral Blood Using a Highly Sensitive Fluorometric Detection Device Without Hemolysis.
  Zhang R, Inagawa H, Takahashi M, Kawanishi H, Kazumura K, Tsuchiya H, Morishita N, Kobayashi Y, Masaki T, Kobara H, Soma GI. Anticancer Res. 2017 Jul;37(7):3897-3903.
• Characterization of the O-antigen polysaccharide derived from Pantoea agglomerans IG1 lipopolysaccharide.
  Hashimoto M, Satou R, Ozono M, Inagawa H, Soma GI. Carbohydr Res. 2017 Sep 8;449:32-36.
• Effects of 3 months continuous intake of supplement containing Pantoea agglomerans LPS to maintain normal bloodstream in adults: Parallel double-blind randomized controlled study.
  Nakata Y, Kohchi C, Ogawa K, Nakamoto T, Yoshimura H, Soma GI. Food Sci Nutr. 2017 Nov 20;6(1):197-206.
• 「健康で美しい肌を導く新しい機能性素材LPS」.
  稲川裕之. FOOD STYLE 21, 2017/05/01発行, 240号.
• 「食品の健康機能を評価する新しいシステムの開発」.
  稲川裕之. FOOD STYLE 21, 2017/10/01発行, 245号.
• 「生体内異物に着目したホメオスタシス維持機能の評価法開発の意義」.
  稲川裕之、杣源一郎. 生物工学会誌, 2017, vol. 95, 6, p321.
• Measuring body balance for diet assessment.
  Soma G. Nature Spotlight on Food Science in Japan, Nature, 2017, March 30, vol 543, No 7647.

2016年

• Development of an Evaluation Device for Phagocytic Activity of New Phagocytes Using Simple and pH-sensitive Particles that Do Not Require Pre-treatment.
  Zhang R, Kobayashi Y, Kazumura K, Tsuchiya H, Morishita N, Inagawa H, Soma G. Anticancer Res. 2016 Jul;36(7):3613-8.
• 「変自然免疫を制御するパントエア菌LPS の飲水投与による犬の肥満抑制効果」.
  小久保貴史、石原裕子、古賀浩一、神明良典、高木俊輔、萩田倫子、小椋 功、小早川克史、稲川裕之. InfoVets, 2016. 5, No.181.
• Clinical Effects of Orally Administered Lipopolysaccharide Derived from Pantoea agglomerans on Malignant Tumors.
  Morishima A, Inagawa H. Anticancer Res. 2016 Jul;36(7):3747-51.
• Effect of Lipopolysaccharide Derived from Pantoea agglomerans on the Phagocytic Activity of Amyloid β by Primary Murine Microglial Cells.
  Kobayashi Y, Inagawa H, Kohchi C, Okazaki K, Zhang R, Soma G. Anticancer Res. 2016 Jul;36(7):3693-8.
• Gene Expression in Lipopolysaccharide-treated Human Monocytes Following Interaction with Hepatic Cancer Cells.
  Honda T, Inagawa H. Anticancer Res. 2016 Jul;36(7):3699-704.
• Immunopotentiator from Pantoea agglomerans 1 (IP-PA1) Promotes Murine Hair Growth and Human Dermal Papilla Cell Gene Expression.
  Wakame K, Okawa H, Komatsu KI, Nakata A, Sato K, Ingawa H, Kohchi C, Nishizawa T, Soma G. Anticancer Res. 2016 Jul;36(7):3687-92.
• Dewaxed Brown Rice Contains a Significant Amount of Lipopolysaccharide Pointing to Macrophage Activation via TLRs.
  Inagawa H, Saika T, Nisizawa T, Kohchi C, Uenobe M, Soma G. Anticancer Res. 2016 Jul;36(7):3599-605.
• Primed Activation of Macrophages by Oral Administration of Lipopolysaccharide Derived from Pantoea agglomerans.
  Inagawa H, Kobayashi Y, Kohchi C, Zhang R, Shibasaki Y, Soma G. In Vivo. 2016 May-Jun;30(3):205-11.
• 「自然免疫を活性化する『免疫ビタミン・LPS』」.
  稲川裕之、杣源一郎. FOOD STYLE 21, 2016/12/01発行, 235号.
• 「LPSを食品の機能成分として見る世界」.
  稲川裕之. 食品加工、2016, vol. 36, No. 2.
• 「マクロファージの生体内異物排除機構に着目した健康維持」.
  稲川裕之. 食品加工、2016, vol. 36, No. 1.

2015年

• Immunopotentiator from Pantoea agglomerans Prevents Atopic Dermatitis Induced by Dermatophagoides farinae Extract in NC/Nga Mouse.
  Wakame K, Komatsu K, Inagawa H, Nishizawa T. Anticancer Res. 2015 Aug;35(8):4501-8.
• Effects of the Subaleurone Layer of Rice on Macrophage Activation and Protection of Pollen Allergy in a Murine Model.
  Tamura Y, Inagawa H, Nakata Y, Kohchi C, Soma G. Anticancer Res. 2015 Aug;35(8):4467-72.
• Oral Administration of Lipopolysaccharide of Acetic Acid Bacteria Protects Pollen Allergy in a Murine Model.
  Amano S, Inagawa H, Nakata Y, Ohmori M, Kohchi C, Soma G. Anticancer Res. 2015 Aug;35(8):4509-14.
• Innate Immunity Activated by Oral Administration of LPSp Is Phylogenetically Preserved and Developed in Broiler Chickens.
  Komori T, Saito K, Sawa N, Shibasaki Y, Kohchi C, Soma G, Inagawa H. Anticancer Res. 2015 Aug;35(8):4461-6.
• Molecular Response of Human Monocytes Following Interaction with Colon Cancer Cells by Pre-treatment with Low-dose Lipopolysaccharide.
  Honda T, Inagawa H. Anticancer Res. 2015 Aug;35(8):4473-7.
• Methods to Prevent or Treat Refractory Diseases by Focusing on Intestinal Microbes Using LPS and Macrophages.
  Soma G, Inagawa H. Anticancer Res. 2015 Aug;35(8):4393-6.
• 「”免疫ビタミン”LPSを生かした健康社会の実現」.
  稲川裕之、杣源一郎. 食品加工技術, 2015, vol35, No. 2, p13-23.
• 「抗菌剤のDDS　結核治療を目的とした肺胞マクロファージ標的経肺吸収型リファンピシン含有微粒子の開発」.
  稲川裕之、牧野公子. 日本防菌防黴学会誌, 2015, 7月10日発行, 43(7), p343-348.

2014年

• Expression of chemotaxis- and angiogenesis-related factors in human monocytes following interaction with colon cancer cells is suppressed by low-dose lipopolysaccharide.
  Honda T, Inagawa H, Yamamoto I. Anticancer Res. 2014 Aug;34(8):4609-13.
• Pantoea agglomerans lipopolysaccharide maintains bone density in premenopausal women: a randomized, double-blind, placebo-controlled trial.
  Nakata K, Nakata Y, Inagawa H, Nakamoto T, Yoshimura H, Soma G. Food Sci Nutr. 2014 Nov;2(6):638-46.
• Usefulness of oral administration of lipopolysaccharide for disease prevention through the induction of priming in macrophages.
  Inagawa H, Kohchi C, Soma G. Anticancer Res. 2014 Aug;34(8):4497-501.
• 「マクロファージとLPS（糖脂質）の有用性」.
  稲川裕之、杣源一郎. Bio Clinica 29(4), 2014, p373-381.

2013年

• Induction of nitric oxide production in RAW264.7 cells under serum-free conditions by O-antigen polysaccharide of lipopolysaccharide.
  Kadowaki T, Ohno S, Taniguchi Y, Inagawa H, Kohchi C, Soma G. Anticancer Res. 2013 Jul;33(7):2875-9.
• Angiogenesis-, metastasis- and signaling pathway-related factor dynamics in human colon cancer cells following interaction with monocytes.
  Honda T, Yamamoto I, Inagawa H. Anticancer Res. 2013 Jul;33(7):2895-900.
• Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio).
  Kadowaki T, Yasui Y, Nishimiya O, Takahashi Y, Kohchi C, Soma G, Inagawa H. Fish Shellfish Immunol. 2013 Jun;34(6):1569-75.
• 「免疫機能を制御する食品素材の研究動向」.
  稲川裕之、杣源一郎. Food STYLE 21, 2013, vol. 17, No. 6: p38-41.
• 「食べる自然免疫ことはじめ」.
  稲川裕之. Food Style 21, 2013.9~2014.2 連載, vol 17 No.9~Vol 18 No.2.
• 「自然免疫を正誤して健康を増進する亜糊紛層残存米「金芽米」のポテンシャル」.
  稲川裕之. ジャパンフードサイエンス, 2013, vol 52, No. 10, p55-59.
• Effects of interactions between intestinal microbiota and intestinal macrophages on health.
  Nakata K, Yamamoto M, Inagawa H, Soma G. Anticancer Res. 2013 Jul;33(7):2849-53.

2012年

• 「乳酸菌・キノコ抽出物含有食品の免疫調整作用および安全性の検証」.
  中本尊、稲川裕之、西澤孝志、吉村寛志. 臨床と研究、2012,　10月, 89巻10号.
• 「小動物に対するアトピー・アレルギー性疾患への新しいアプローチ方法」.
  稲川裕之、河内千恵、杣源一郎、木田晃子、大川博、澤則之. Companion Animal Practice, 2012, 5.
• Genome sequence of Pantoea agglomerans strain IG1.
  Matsuzawa T, Mori K, Kadowaki T, Shimada M, Tashiro K, Kuhara S, Inagawa H, Soma G, Takegawa K.　 J Bacteriol. 2012 Mar;194(5):1258-9.
• 「サラシア茶とIP-PA1混合物による糖尿病予防効果」.
  中田和江、谷口芳枝、吉岡典子、吉田彩、稲川裕之、中本尊、吉村寛志、三宅信一郎、河内千恵、黒木正秀、杣源一郎. New Food Industry, 2012, vol. 54, No. 2: p25-35.
• Galectin-9 signaling prolongs survival in murine lung-cancer by inducing macrophages to differentiate into plasmacytoid dendritic cell-like macrophages.
  Kadowaki T, Arikawa T, Shinonaga R, Oomizu S, Inagawa H, Soma G, Niki T,　Hirashima M. Clin Immunol. 2012 Mar;142(3):296-307.
• The involvement of O-antigen polysaccharide in lipopolysaccharide in macrophage activation.
  Shimada M, Kadowaki T, Taniguchi Y, Inagawa H, Okazaki K, Soma G. Anticancer Res. 2012 Jun;32(6):2337-41.
• Reconsideration of macrophage and dendritic cell classification.
  Kadowaki T, Shimada M, Inagawa H, Kohchi C, Hirashima M, Soma G. Anticancer Res. 2012 Jun;32(6):2257-61.
• Biological response modifiers used in cancer biotherapy.
  Kuroki M, Miyamoto S, Morisaki T, Yotsumoto F, Shirasu N, Taniguchi Y, Soma G. Anticancer Res. 2012 Jun;32(6):2229-33.

2011年

• A mixture of Salacia oblonga extract and IP-PA1 reduces fasting plasma glucose (FPG) and low-density lipoprotein (LDL) cholesterol levels.
  Nakata K, Taniguchi Y, Yoshioka N, Yoshida A, Inagawa H, Nakamoto T, Yoshimura H, Miyake S, Kohchi C, Kuroki M, Soma G. Nutr Res Pract. 2011 Oct;5(5):435-42.
• Oral administration of immunopotentiator from Pantoea agglomerans 1 (IP-PA1) improves the survival of B16 melanoma-inoculated model mice.
  Hebishima T, Matsumoto Y, Watanabe G, Soma G, Kohchi C, Taya K, Hayashi Y, Hirota Y. Exp Anim. 2011;60(2):101-9.
• Differential expression of mRNA in human monocytes following interaction with human colon cancer cells.
  Honda T, Inagawa H, Yamamoto I. Anticancer Res. 2011 Jul;31(7):2493-7.
• Functional characterization of lipopolysaccharide derived from symbiotic bacteria in rice as a macrophage-activating substance.
  Kadowaki T, Inagawa H, Kohchi C, Hirashima M, Soma G. Anticancer Res. 2011 Jul;31(7):2467-76.
• WT1 peptide vaccine stabilized intractable ovarian cancer patient for one year: a case report.
  Dohi S, Ohno S, Ohno Y, Takakura M, Kyo S, Soma G, Sugiyama H, Inoue M. Anticancer Res. 2011 Jul;31(7):2441-5.
• Anti-lipopolysaccharide factor evokes indirect killing of virulent bacteria in kuruma prawn.
  Kadowaki T, Inagawa H, Kohchi C, Nishizawa T, Takahashi Y, Soma G. In Vivo. 2011 Sep-Oct;25(5):741-4.
• Oral administration of lipopolysaccharides for the prevention of various diseases: benefit and usefulness.
  Inagawa H, Kohchi C, Soma G. Anticancer Res. 2011 Jul;31(7):2431-6.
• Lipopolysaccharide IP-PA1 from Pantoea agglomerans prevents suppression of macrophage function in stress-induced diseases.
  Nakata K, Inagawa H, Soma G. Anticancer Res. 2011 Jul;31(7):2437-40.
• 「自然免疫による放射線内部被爆障害の低減」.
  稲川裕之、河内千恵、杣源一郎. Food STYLE 21, 2011, vol. 15, No. 11: p1-4.
• 「LPS(糖脂質）のアレルギー性疾患への有用性」.
  稲川裕之、河内千恵、杣源一郎. Food STYLE 21, 2011, vol. 15, No. 11: p45-47.
• 「免疫増強および自然治癒力強化を特徴とする安全安心な糖脂質素材の開発」.
  河内千恵、西澤孝志、稲川裕之、杣源一郎. 食品工業, 2011, 1.30, p52-61.

2010年

• Protective effects of the immunopotentiator from Pantoea agglomerans 1 on chemotherapeutic agent-induced macrophage growth inhibition.
  Hebishima T, Matsumoto Y, Watanabe G, Soma G, Kohchi C, Taya K, Hayashi Y, Hirota Y. Anticancer Res. 2010 Jun;30(6):2033-40.
• The relationship between clinicopathological factors and the reduction of pyrimidine nucleoside phosphorylase activity after preoperative administration of 5'-deoxy-5-fluorouridine.
  Honda T, Inagawa H, Nishizawa T, Yoshimura H, Yamamoto I, Soma G. Anticancer Res. 2010 Aug;30(8):3207-11.
• Antitumor effect of inhalatory lipopolysaccharide and synergetic effect in combination with cyclophosphamide.
  Hirota K, Oishi Y, Taniguchi H, Sawachi K, Inagawa H, Kohchi C, Soma G, Terada H. Anticancer Res. 2010 Aug;30(8):3129-34.
• Cytotoxic effects of activated alveolar macrophages on lung carcinoma cells via cell-to-cell contact and nitric oxide.
  Sawachi K, Shimada Y, Taniguchi H, Hirota K, Inagawa H, Kohchi C, Soma G, Makino K, Terada H. Anticancer Res. 2010 Aug;30(8):3135-41.
• Lipopolysaccharide-activated alveolar macrophages having cytotoxicity toward lung tumor cells through cell-to-cell binding-dependent mechanism.
  Taniguchi H, Shimada Y, Sawachi K, Hirota K, Inagawa H, Kohchi C, Soma G, Makino K, Terada H. Anticancer Res. 2010 Aug;30(8):3159-65.
• Preparation of lipopolysaccharide derived from Pantoea agglomerans labeled with fluorescence as a tracer for kinetics analysis.
  Kadowaki T, Inagawa H, Kohchi C, Hirashima M, Soma G. Anticancer Res. 2010 Aug;30(8):3151-7.
• Immune recovery effects of immunopotentiator from Pantoea agglomerans 1 (IP-PA1) on low antibody productions in response to Salmonella enteritidis vaccine and sheep red blood cells in dexamethasone-treated stressed chicken models.
  Hebishima T, Matsumoto Y, Soma G, Kohchi C, Watanabe G, Taya K, Hayashi Y, Hirota Y. J Vet Med Sci. 2010 Apr;72(4):435-42.
• Delivery of rifampicin-PLGA microspheres into alveolar macrophages is promising for treatment of tuberculosis.
  Hirota K, Hasegawa T, Nakajima T, Inagawa H, Kohchi C, Soma G, Makino K, Terada H. J Control Release. 2010 Mar 19;142(3):339-46.
• WT1 expression correlates with angiogenesis in endometrial cancer tissue.
  Dohi S, Ohno S, Ohno Y, Kyo S, Soma G, Sugiyama H, Inoue M. Anticancer Res. 2010 Aug;30(8):3187-92.
• Lymphokine-activated killer cell therapy combined with high-dose glucocorticoid showed clinical efficacy towards advanced lung carcinoma.
  Kato M, Goto S, Soma G. Anticancer Res. 2010 Aug;30(8):3125-8.
• Recovery from immunosuppression-related disorders in humans and animals by IP-PA1, an edible lipopolysaccharide.
  Hebishima T, Matsumoto Y, Watanabe G, Soma G, Kohchi C, Taya K, Hayashi Y, Hirota Y. Anticancer Res. 2010 Aug;30(8):3113-8.
• Cytotoxic and Protective Activity of Nitric Oxide in Cancers.
  Inagawa H, Kohchi C, Soma G. In: Benjamin Bonavida (Eds.), Nitric Oxide (NO) and Cancer, 103-132, 2010.
• 「糖脂質の再発見　-環境から与えられる優れた免疫制御物質-」.
  河内千恵、西澤孝志、稲川裕之、杣源一郎. ケミカルエンジニヤリング, 2010, 4月号, p290-294.

1992年～2009年

• 文献リスト（1992年～2009年）PDFファイル